Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

African swine fever virus (ASFV) is contagious and can cause highly lethal disease in pigs. ASFV DNA ligase (AsfvLIG) is one of the most error-prone ligases identified to date; it catalyzes DNA joining reaction during DNA repair process of ASFV and plays important roles in mutagenesis of the viral g...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Chen, Yiqing, Liu, Hehua, Yang, Chun, Gao, Yanqing, Yu, Xiang, Chen, Xi, Cui, Ruixue, Zheng, Lina, Li, Suhua, Li, Xuhang, Ma, Jinbiao, Huang, Zhen, Li, Jixi, Gan, Jianhua
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344480/
https://ncbi.nlm.nih.gov/pubmed/30674878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08296-w
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