Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

African swine fever virus (ASFV) is contagious and can cause highly lethal disease in pigs. ASFV DNA ligase (AsfvLIG) is one of the most error-prone ligases identified to date; it catalyzes DNA joining reaction during DNA repair process of ASFV and plays important roles in mutagenesis of the viral g...

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Publicado no:Nat Commun
Principais autores: Chen, Yiqing, Liu, Hehua, Yang, Chun, Gao, Yanqing, Yu, Xiang, Chen, Xi, Cui, Ruixue, Zheng, Lina, Li, Suhua, Li, Xuhang, Ma, Jinbiao, Huang, Zhen, Li, Jixi, Gan, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344480/
https://ncbi.nlm.nih.gov/pubmed/30674878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08296-w
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