Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

African swine fever virus (ASFV) is contagious and can cause highly lethal disease in pigs. ASFV DNA ligase (AsfvLIG) is one of the most error-prone ligases identified to date; it catalyzes DNA joining reaction during DNA repair process of ASFV and plays important roles in mutagenesis of the viral g...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Chen, Yiqing, Liu, Hehua, Yang, Chun, Gao, Yanqing, Yu, Xiang, Chen, Xi, Cui, Ruixue, Zheng, Lina, Li, Suhua, Li, Xuhang, Ma, Jinbiao, Huang, Zhen, Li, Jixi, Gan, Jianhua
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344480/
https://ncbi.nlm.nih.gov/pubmed/30674878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08296-w
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