Structural insights into DNA degradation by human mitochondrial nuclease MGME1

Mitochondrial nucleases play important roles in accurate maintenance and correct metabolism of mtDNA, the own genetic materials of mitochondria that are passed exclusively from mother to child. MGME1 is a highly conserved DNase that was discovered recently. Mutations in MGME1-coding gene lead to sev...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yang, Chun, Wu, Ruiqi, Liu, Hehua, Chen, Yiqing, Gao, Yanqing, Chen, Xi, Li, Yangyang, Ma, Jinbiao, Li, Jixi, Gan, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237815/
https://ncbi.nlm.nih.gov/pubmed/30247721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky855
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