Structural insights into DNA degradation by human mitochondrial nuclease MGME1

Mitochondrial nucleases play important roles in accurate maintenance and correct metabolism of mtDNA, the own genetic materials of mitochondria that are passed exclusively from mother to child. MGME1 is a highly conserved DNase that was discovered recently. Mutations in MGME1-coding gene lead to sev...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Yang, Chun, Wu, Ruiqi, Liu, Hehua, Chen, Yiqing, Gao, Yanqing, Chen, Xi, Li, Yangyang, Ma, Jinbiao, Li, Jixi, Gan, Jianhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237815/
https://ncbi.nlm.nih.gov/pubmed/30247721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky855
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