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Structural insights into DNA degradation by human mitochondrial nuclease MGME1

Mitochondrial nucleases play important roles in accurate maintenance and correct metabolism of mtDNA, the own genetic materials of mitochondria that are passed exclusively from mother to child. MGME1 is a highly conserved DNase that was discovered recently. Mutations in MGME1-coding gene lead to sev...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Yang, Chun, Wu, Ruiqi, Liu, Hehua, Chen, Yiqing, Gao, Yanqing, Chen, Xi, Li, Yangyang, Ma, Jinbiao, Li, Jixi, Gan, Jianhua
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237815/
https://ncbi.nlm.nih.gov/pubmed/30247721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky855
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