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Structural insights into DNA degradation by human mitochondrial nuclease MGME1

Mitochondrial nucleases play important roles in accurate maintenance and correct metabolism of mtDNA, the own genetic materials of mitochondria that are passed exclusively from mother to child. MGME1 is a highly conserved DNase that was discovered recently. Mutations in MGME1-coding gene lead to sev...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Yang, Chun, Wu, Ruiqi, Liu, Hehua, Chen, Yiqing, Gao, Yanqing, Chen, Xi, Li, Yangyang, Ma, Jinbiao, Li, Jixi, Gan, Jianhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237815/
https://ncbi.nlm.nih.gov/pubmed/30247721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky855
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