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The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway
In nucleotide incision repair (NIR), an endonuclease nicks oxidatively damaged DNA in a DNA glycosylase-independent manner, providing the correct ends for DNA synthesis coupled to the repair of the remaining 5′-dangling modified nucleotide. This mechanistic feature is distinct from DNA glycosylase-m...
Tallennettuna:
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2004
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373275/ https://ncbi.nlm.nih.gov/pubmed/14704345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh165 |
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