The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway
In nucleotide incision repair (NIR), an endonuclease nicks oxidatively damaged DNA in a DNA glycosylase-independent manner, providing the correct ends for DNA synthesis coupled to the repair of the remaining 5′-dangling modified nucleotide. This mechanistic feature is distinct from DNA glycosylase-m...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14704345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh165 |
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