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Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7
Toll-like receptor (TLR)-7 agonists show prominent immunostimulatory activities. The synthesis of a TLR7-active N(1)-(4-aminomethyl)benzyl substituted imidazoquinoline 5d served as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. Fluorescence m...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957514/ https://ncbi.nlm.nih.gov/pubmed/20933417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.09.093 |
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