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Toll-Like Receptor (TLR)-7 and -8 Modulatory Activities of Dimeric Imidazoquinolines

Toll-like receptors (TLRs) are pattern recognition receptors that recognize specific molecular patterns present in molecules that are broadly shared by pathogens, but are structurally distinct from host molecules. The TLR7-agonistic imidazoquinolines are of interest as vaccine adjuvants given their...

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Main Authors: Shukla, Nikunj M., Mutz, Cole A., Malladi, Subbalakshmi S., Warshakoon, Hemamali J., Balakrishna, Rajalakshmi, David, Sunil A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276691/
https://ncbi.nlm.nih.gov/pubmed/22239408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2010207
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