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Potent Adjuvanticity of a Pure TLR7-Agonistic Imidazoquinoline Dendrimer

Engagement of toll-like receptors (TLRs) serve to link innate immune responses with adaptive immunity and can be exploited as powerful vaccine adjuvants for eliciting both primary and anamnestic immune responses. TLR7 agonists are highly immunostimulatory without inducing dominant proinflammatory cy...

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Détails bibliographiques
Auteurs principaux: Shukla, Nikunj M., Salunke, Deepak B., Balakrishna, Rajalakshmi, Mutz, Cole A., Malladi, Subbalakshmi S., David, Sunil A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429503/
https://ncbi.nlm.nih.gov/pubmed/22952720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043612
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