Potent Adjuvantic Activity of a CCR1-agonistic Bis-Quinoline

A bis-quinoline compound, (7-chloro-N-(4-(7-chloroquinolin-4-ylamino)butyl)quinolin-4-amine; RE-660) was found to have C-C chemokine receptor type 1 (CCR1)-agonistic properties.RE-660 displayed strong adjuvantic activity in mice when co-administered with bovine α-lactalbumin used as a model subunit...

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Main Authors: Ukani, Rehman, Lewis, Tyler C., Day, Timothy P., Wu, Wenyan, Malladi, Subbalakshmi S., Warshakoon, Hemamali J., David, Sunil A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248955/
https://ncbi.nlm.nih.gov/pubmed/22104149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.11.014
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