Structure-Activity Relationships in Toll-like Receptor 2-Agonists Leading to Simplified Monoacyl Lipopeptides

Toll-like receptor 2-agonistic lipopeptides typified by S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-R-cysteinyl-S-serine (PAM(2)CS) compounds are potential vaccine adjuvants. In continuation of previously reported structure-activity relationships on this chemotype, we have determined that at least one ac...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Agnihotri, Geetanjali, Crall, Breanna M., Lewis, Tyler C., Day, Timothy P., Balakrishna, Rajalakshmi, Warshakoon, Hemamali J., Malladi, Subbalakshmi S., David, Sunil A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228886/
https://ncbi.nlm.nih.gov/pubmed/22007676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201071e
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items