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Structure-Activity Relationships in Human Toll-like Receptor 7-Active Imidazoquinoline Analogues

Engagement of toll-like receptors serve to link innate immune responses with adaptive immunity and can be exploited as powerful vaccine adjuvants for eliciting both primary and anamnestic immune responses. TLR7 agonists are highly immunostimulatory without inducing dominant proinflammatory cytokine...

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Detalhes bibliográficos
Main Authors: Shukla, Nikunj M., Malladi, Subbalakshmi S., Mutz, Cole A., Balakrishna, Rajalakshmi, David, Sunil A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895411/
https://ncbi.nlm.nih.gov/pubmed/20481492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100358c
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