Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the children’s oncology group

Aberrant activation of Akt is a common finding in adult malignant gliomas, resulting in most cases from mutations or deletions involving PTEN, which allows constitutive Akt phosphorylation. In contrast, we have previously reported that pediatric malignant gliomas, which are morphologically similar t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pollack, Ian F., Hamilton, Ronald L., Murdoch, Geoffrey H., Burger, Peter C., Brat, Daniel J., Rosenblum, Marc K., Nikiforova, Marina N., Holmes, Emiko J., Zhou, Tianni, Cohen, Kenneth J., Jakacki, Regina I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954435/
https://ncbi.nlm.nih.gov/pubmed/20607350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0297-3
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge