Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the children’s oncology group

Aberrant activation of Akt is a common finding in adult malignant gliomas, resulting in most cases from mutations or deletions involving PTEN, which allows constitutive Akt phosphorylation. In contrast, we have previously reported that pediatric malignant gliomas, which are morphologically similar t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Pollack, Ian F., Hamilton, Ronald L., Murdoch, Geoffrey H., Burger, Peter C., Brat, Daniel J., Rosenblum, Marc K., Nikiforova, Marina N., Holmes, Emiko J., Zhou, Tianni, Cohen, Kenneth J., Jakacki, Regina I.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954435/
https://ncbi.nlm.nih.gov/pubmed/20607350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0297-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars