Caricamento...

Cardiomyopathy-linked myosin regulatory light chain mutations disrupt myosin strain-dependent biochemistry

Familial hypertrophic cardiomyopathy (FHC) is caused by mutations in sarcomeric proteins including the myosin regulatory light chain (RLC). Two such FHC mutations, R58Q and N47K, located near the cationic binding site of the RLC, have been identified from population studies. To examine the molecular...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Greenberg, Michael J., Kazmierczak, Katarzyna, Szczesna-Cordary, Danuta, Moore, Jeffrey R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951453/
https://ncbi.nlm.nih.gov/pubmed/20855589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009619107
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !