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Pseudophosphorylation of cardiac myosin regulatory light chain: a promising new tool for treatment of cardiomyopathy

Many genetic mutations in sarcomeric proteins, including the cardiac myosin regulatory light chain (RLC) encoded by the MYL2 gene, have been implicated in familial cardiomyopathies. Yet, the molecular mechanisms by which these mutant proteins regulate cardiac muscle mechanics in health and disease r...

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Dettagli Bibliografici
Pubblicato in:Biophys Rev
Autori principali: Yadav, Sunil, Szczesna-Cordary, Danuta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418495/
https://ncbi.nlm.nih.gov/pubmed/28510043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-017-0248-8
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