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Pseudophosphorylation of cardiac myosin regulatory light chain: a promising new tool for treatment of cardiomyopathy

Many genetic mutations in sarcomeric proteins, including the cardiac myosin regulatory light chain (RLC) encoded by the MYL2 gene, have been implicated in familial cardiomyopathies. Yet, the molecular mechanisms by which these mutant proteins regulate cardiac muscle mechanics in health and disease r...

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Detalhes bibliográficos
Publicado no:Biophys Rev
Principais autores: Yadav, Sunil, Szczesna-Cordary, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418495/
https://ncbi.nlm.nih.gov/pubmed/28510043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-017-0248-8
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