Wordt geladen...
Enantioselective Total Synthesis of (+)-Largazole, a Potent Inhibitor of Histone Deacetylase
[Image: see text] An enantioselective total synthesis of cytotoxic natural product, (+)-largazole (1) is described. It is a potent histone deacetylase inhibitor. Our synthesis is convergent and involves the assembly of thiazole 3-derived carboxylic acid with amino ester 4 followed by cycloamidation...
Bewaard in:
| Hoofdauteurs: | , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945909/ https://ncbi.nlm.nih.gov/pubmed/18662003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8014623 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|