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Enantioselective Total Synthesis of (−)-Zampanolide, a Potent Microtubule-Stabilizing Agent

[Image: see text] An enantioselective total synthesis of zampanolide has been accomplished using a novel DDQ/Brønsted acid catalyzed cyclization as the key reaction. The synthesis features cross-metathesis to construct the tri-substituted olefin and a ring-closing metathesis to form the macrolactone...

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Bibliografische gegevens
Hoofdauteurs: Ghosh, Arun K., Cheng, Xu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153378/
https://ncbi.nlm.nih.gov/pubmed/21749032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201626h
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