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Enantioselective Total Synthesis of (−)-Zampanolide, a Potent Microtubule-Stabilizing Agent
[Image: see text] An enantioselective total synthesis of zampanolide has been accomplished using a novel DDQ/Brønsted acid catalyzed cyclization as the key reaction. The synthesis features cross-metathesis to construct the tri-substituted olefin and a ring-closing metathesis to form the macrolactone...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3153378/ https://ncbi.nlm.nih.gov/pubmed/21749032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201626h |
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