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Enantioselective Total Synthesis of (+)-Lithospermic Acid

[Image: see text] An enantioselective synthesis of (+)-lithospermic acid, a potent anti-HIV agent, has been accomplished in a convergent manner in 9 steps. The synthesis features an enantioselective intramolecular oxa-Michael addition catalyzed by a quinidine derivative, a hypervalent iodine-mediate...

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Detalhes bibliográficos
Main Authors: Ghosh, Arun K., Cheng, Xu, Zhou, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482163/
https://ncbi.nlm.nih.gov/pubmed/22978790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol302273r
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