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Enantioselective total synthesis of macrolide (+)-neopeltolide
The asymmetric total synthesis of the anti-proliferative macrolide (+)-neopeltolide has been completed. The stereochemically defined trisubstituted tetrahydropyran ring was constructed via a catalytic hetero-Diels–Alder reaction creating two new chiral centers in a highly diastereoselective manner....
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| Publicado no: | Org Biomol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037168/ https://ncbi.nlm.nih.gov/pubmed/24121457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob41541d |
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