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Total synthesis of neopeltolide and analogs

Neopeltolide, a potent cytotoxin from a Carribean sponge, was synthesized through a brief sequence that highlights the use of ethers as oxocarbenium ion precursors. Other key steps include an acid-mediated etherification and sequence that features a Sonogashira reaction, an intramolecular alkyne hyd...

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Détails bibliographiques
Auteurs principaux: Cui, Yubo, Tu, Wangyang, Floreancig, Paul E.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917233/
https://ncbi.nlm.nih.gov/pubmed/20697460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.03.066
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