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Total synthesis of neopeltolide and analogs
Neopeltolide, a potent cytotoxin from a Carribean sponge, was synthesized through a brief sequence that highlights the use of ethers as oxocarbenium ion precursors. Other key steps include an acid-mediated etherification and sequence that features a Sonogashira reaction, an intramolecular alkyne hyd...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917233/ https://ncbi.nlm.nih.gov/pubmed/20697460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.03.066 |
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