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Synthesis and Biological Evaluation of Neopeltolide and Analogs

The synthesis of neopeltolide analogs that contain variations in the oxazole-containing side chain and in the macrolide core are reported along with the GI(50) values for these compounds against MCF7, HCT-116, and p53 knockout HCT-116 cell lines. Although biological activity is sensitive to changes...

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Hlavní autoři: Cui, Yubo, Balachandran, Raghavan, Day, Billy W., Floreancig, Paul E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308185/
https://ncbi.nlm.nih.gov/pubmed/22329423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2023685
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