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Synthesis and Biological Evaluation of Neopeltolide and Analogs
The synthesis of neopeltolide analogs that contain variations in the oxazole-containing side chain and in the macrolide core are reported along with the GI(50) values for these compounds against MCF7, HCT-116, and p53 knockout HCT-116 cell lines. Although biological activity is sensitive to changes...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308185/ https://ncbi.nlm.nih.gov/pubmed/22329423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2023685 |
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