Synthesis and biological evaluation of (−)-dictyostatin and stereoisomers

Total syntheses of (−)-dictyostatin, 6,16-bis-epi-dictyostatin, 6,14,19-tris-epi-dictyostatin and a number of other isomers and analogs are reported. Three main fragments—top, middle and bottom—were first assembled and then joined by olefination or anionic addition reactions. After appending the two...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Shin, Youseung, Fournier, Jean-Hugues, Brückner, Arndt, Madiraju, Charitha, Balachandran, Raghavan, Raccor, Brianne S., Edler, Michael C., Hamel, Ernest, Sikorski, Rachel P., Vogt, Andreas, Day, Billy W., Curran, Dennis P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000856/
https://ncbi.nlm.nih.gov/pubmed/18728696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.05.033
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