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Efficient syntheses of 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, two potent new microtubule-stabilizing agents

The dictyostatins are powerful microtubule-stabilizing agents that have shown antiproliferative activity against a variety of human cancer cell lines. Two highly active analogs of dictyostatin, 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, were prepared by a new streamlined total s...

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Hlavní autoři: Jiménez, María, Zhu, Wei, Vogt, Andreas, Day, Billy W, Curran, Dennis P
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201051/
https://ncbi.nlm.nih.gov/pubmed/22043248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.161
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