Synthesis and biological evaluation of (−)-dictyostatin and stereoisomers

Total syntheses of (−)-dictyostatin, 6,16-bis-epi-dictyostatin, 6,14,19-tris-epi-dictyostatin and a number of other isomers and analogs are reported. Three main fragments—top, middle and bottom—were first assembled and then joined by olefination or anionic addition reactions. After appending the two...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Shin, Youseung, Fournier, Jean-Hugues, Brückner, Arndt, Madiraju, Charitha, Balachandran, Raghavan, Raccor, Brianne S., Edler, Michael C., Hamel, Ernest, Sikorski, Rachel P., Vogt, Andreas, Day, Billy W., Curran, Dennis P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000856/
https://ncbi.nlm.nih.gov/pubmed/18728696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.05.033
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk