Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51)

Purified Candida albicans sterol 14-α demethylase (CaCYP51) bound the CYP51 substrates lanosterol and eburicol, producing type I binding spectra with K(s) values of 11 and 25 μM, respectively, and a K(m) value of 6 μM for lanosterol. Azole binding to CaCYP51 was “tight” with both the type II spectra...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Warrilow, Andrew G. S., Martel, Claire M., Parker, Josie E., Melo, Nadja, Lamb, David C., Nes, W. David, Kelly, Diane E., Kelly, Steven L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944560/
https://ncbi.nlm.nih.gov/pubmed/20625155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00587-10
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars