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Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints
Family B G protein-coupled receptors include several potentially important drug targets, yet our understanding of the molecular basis of ligand binding to and activation of these receptors is incomplete. While NMR and crystal structures exist for peptide ligand-associated amino-terminal domains of s...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943047/ https://ncbi.nlm.nih.gov/pubmed/20813522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.08.062 |
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