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Insights into the impact of phenolic residue incorporation at each position along secretin for receptor binding and biological activity

Understanding of the structural importance of each position along a peptide ligand can provide important insights into the molecular basis for its receptor binding and biological activity. This has typically been evaluated using serial replacement of each natural residue with an alanine. In the curr...

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Hlavní autoři: Dong, Maoqing, Pinon, Delia I., Miller, Laurence J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534899/
https://ncbi.nlm.nih.gov/pubmed/23142313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2012.10.001
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