Importance of Each Residue within Secretin for Receptor Binding and Biological Activity

Secretin is a linear 27-residue peptide hormone that stimulates pancreatic and biliary ductular bicarbonate and water secretion by acting at its family B G protein-coupled receptor. While, like other family members, the carboxyl-terminal region of secretin is most important for high affinity binding...

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Hlavní autoři: Dong, Maoqing, Le, Angela, Te, Jerez A., Pinon, Delia I., Bordner, Andrew J., Miller, Laurence J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071462/
https://ncbi.nlm.nih.gov/pubmed/21388146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200133u
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