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Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints
Family B G protein-coupled receptors include several potentially important drug targets, yet our understanding of the molecular basis of ligand binding to and activation of these receptors is incomplete. While NMR and crystal structures exist for peptide ligand-associated amino-terminal domains of s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943047/ https://ncbi.nlm.nih.gov/pubmed/20813522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.08.062 |
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