Secretin Occupies a Single Protomer of the Homodimeric Secretin Receptor Complex: INSIGHTS FROM PHOTOAFFINITY LABELING STUDIES USING DUAL SITES OF COVALENT ATTACHMENT

The secretin receptor, a prototypic family B G protein-coupled receptor, forms a constitutive homodimeric complex that is stable even in the presence of hormone. Recently, a model of this agonist-bound receptor was built based on high resolution structures reported for amino-terminal domains of othe...

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Detalhes bibliográficos
Main Authors: Dong, Maoqing, Lam, Polo C.-H., Pinon, Delia I., Orry, Andrew, Sexton, Patrick M., Abagyan, Ruben, Miller, Laurence J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843239/
https://ncbi.nlm.nih.gov/pubmed/20100828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.089730
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