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A Fluopol-ABPP HTS Assay to Identify PAD Inhibitors
Protein Arginine Deiminase (PAD) activity is dysregulated in numerous diseases, e.g., Rheumatoid Arthritis. Herein we describe the development of a fluorescence polarization-Activity Based Protein Profiling (fluopol-ABPP) based high throughput screening assay that can be used to identify PAD-selecti...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943038/ https://ncbi.nlm.nih.gov/pubmed/20740228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02634d |
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