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Profiling Protein Arginine Deiminase 4 (PAD4): A novel screen to identify PAD4 inhibitors
Protein Arginine Deiminase 4 (PAD4) has emerged as a leading target for the development of a Rheumatoid Arthritis (RA) pharmaceutical. Herein, we describe the development of a novel screen for PAD4 inhibitors that is based on a PAD4-targeted Activity-Based Protein Profiling reagent, denoted Rhodamin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267747/ https://ncbi.nlm.nih.gov/pubmed/17964793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.10.021 |
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