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Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization
Protein arginine deiminase 4 (PAD4) is a transcriptional coregulator that catalyzes the calcium-dependent conversion of specific arginine residues in proteins to citrulline. Recently, we reported the synthesis and characterization of F-amidine, a potent and bioavailable irreversible inactivator of P...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808342/ https://ncbi.nlm.nih.gov/pubmed/17002273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061180d |
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