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Activity Based Protein Profiling Reagents for Protein Arginine Deiminase 4 (PAD4): Synthesis and in vitro Evaluation of a Fluorescently-labeled Probe

Protein Arginine Deiminase 4 (PAD4), which catalyzes the post-translational conversion of peptidyl-arginine to peptidyl-citrulline, is widely regarded as one of the best new targets for the development of a novel Rheumatoid Arthritis therapeutic. In addition to its presumed role in this disease, PAD...

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Autors principals: Luo, Yuan, Knuckley, Bryan, Bhatia, Monica, Pellechia, Perry J., Thompson, Paul R.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234596/
https://ncbi.nlm.nih.gov/pubmed/17090024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0656907
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