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Activity Based Protein Profiling Reagents for Protein Arginine Deiminase 4 (PAD4): Synthesis and in vitro Evaluation of a Fluorescently-labeled Probe
Protein Arginine Deiminase 4 (PAD4), which catalyzes the post-translational conversion of peptidyl-arginine to peptidyl-citrulline, is widely regarded as one of the best new targets for the development of a novel Rheumatoid Arthritis therapeutic. In addition to its presumed role in this disease, PAD...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234596/ https://ncbi.nlm.nih.gov/pubmed/17090024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0656907 |
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