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Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization

Protein arginine deiminase 4 (PAD4) is a transcriptional coregulator that catalyzes the calcium-dependent conversion of specific arginine residues in proteins to citrulline. Recently, we reported the synthesis and characterization of F-amidine, a potent and bioavailable irreversible inactivator of P...

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Bibliografische gegevens
Hoofdauteurs: Luo, Yuan, Arita, Kyouhei, Bhatia, Monica, Knuckley, Bryan, Lee, Young-Ho, Stallcup, Michael R., Sato, Mamoru, Thompson, Paul R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808342/
https://ncbi.nlm.nih.gov/pubmed/17002273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061180d
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