RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus

EGF induces the translocation of EGF receptor (EGFR) from the cell surface to the nucleus where EGFR activates gene transcription through its binding to an AT-rich sequence (ATRS) of the target gene promoter. However, how EGFR, without a DNA-binding domain, can bind to the gene promoter is unclear....

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Detalhes bibliográficos
Main Authors: Huo, Longfei, Wang, Ying-Nai, Xia, Weiya, Hsu, Sheng-Chieh, Lai, Chien-Chen, Li, Long-Yuan, Chang, Wei-Chao, Wang, Yan, Hsu, Ming-Chuan, Yu, Yung-Luen, Huang, Tzu-Hsuan, Ding, Qingqing, Chen, Chung-Hsuan, Tsai, Chang-Hai, Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941329/
https://ncbi.nlm.nih.gov/pubmed/20802156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000743107
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