The Translocon Sec61β Localized in the Inner Nuclear Membrane Transports Membrane-embedded EGF Receptor to the Nucleus

Accumulating evidence indicates that endocytosis plays an essential role in the nuclear transport of the ErbB family members, such as epidermal growth factor receptor (EGFR) and ErbB-2. Nevertheless, how full-length receptors embedded in the endosomal membrane pass through the nuclear pore complexes...

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Autori principali: Wang, Ying-Nai, Yamaguchi, Hirohito, Huo, Longfei, Du, Yi, Lee, Hong-Jen, Lee, Heng-Huan, Wang, Hongmei, Hsu, Jung-Mao, Hung, Mien-Chie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992305/
https://ncbi.nlm.nih.gov/pubmed/20937808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158659
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