SND3 is the membrane insertase within a distinct SEC61 translocon complex
Abstract During the biogenesis of most eukaryotic integral membrane proteins (IMPs), transmembrane domains are inserted into the endoplasmic reticulum membrane by a dedicated insertase or the SEC61 translocon. The SRP-independent (SND) pathway is the least understood route into the membrane, despite...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-10-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-025-65357-z |
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