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Structural and Functional Profiling of the Lateral Gate of the Sec61 Translocon

The evolutionarily conserved Sec61 translocon mediates the translocation and membrane insertion of proteins. For the integration of proteins into the membrane, the Sec61 translocon opens laterally to the lipid bilayer. Previous studies suggest that the lateral opening of the channel is mediated by t...

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Detalhes bibliográficos
Main Authors: Reithinger, Johannes H., Yim, Chewon, Kim, Sungmin, Lee, Hunsang, Kim, Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140938/
https://ncbi.nlm.nih.gov/pubmed/24753257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533794
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