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Structural and Functional Profiling of the Lateral Gate of the Sec61 Translocon
The evolutionarily conserved Sec61 translocon mediates the translocation and membrane insertion of proteins. For the integration of proteins into the membrane, the Sec61 translocon opens laterally to the lipid bilayer. Previous studies suggest that the lateral opening of the channel is mediated by t...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140938/ https://ncbi.nlm.nih.gov/pubmed/24753257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533794 |
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