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Functional asymmetry within the Sec61p translocon
The Sec61 translocon forms a pore to translocate polypeptide sequences across the membrane and offers a lateral gate for membrane integration of hydrophobic (H) segments. A central constriction of six apolar residues has been shown to form a seal, but also to determine the hydrophobicity threshold f...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839696/ https://ncbi.nlm.nih.gov/pubmed/24191046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318432110 |
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