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The Plug Domain of Yeast Sec61p Is Important for Efficient Protein Translocation, but Is Not Essential for Cell Viability

The Sec61/SecY translocon mediates translocation of proteins across the membrane and integration of membrane proteins into the lipid bilayer. The structure of the translocon revealed a plug domain blocking the pore on the lumenal side. It was proposed to be important for gating the protein conductin...

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Bibliografske podrobnosti
Main Authors: Junne, Tina, Schwede, Torsten, Goder, Veit, Spiess, Martin
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1556385/
https://ncbi.nlm.nih.gov/pubmed/16822836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-03-0200
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