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Sec61p Contributes to Signal Sequence Orientation According to the Positive-Inside Rule

Protein targeting to the endoplasmic reticulum is mediated by signal or signal-anchor sequences. They also play an important role in protein topogenesis, because their orientation in the translocon determines whether their N- or C-terminal sequence is translocated. Signal orientation is primarily de...

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Hlavní autoři: Goder, Veit, Junne, Tina, Spiess, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC363169/
https://ncbi.nlm.nih.gov/pubmed/14668483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0599
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