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Structure of the Sec61 channel opened by a signal sequence
Secreted and integral membrane proteins comprise up to one-third of the biological proteome. These proteins contain hydrophobic signals that direct their translocation across or insertion into the lipid bilayer by the Sec61 protein conducting channel. The molecular basis for how hydrophobic signals...
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| Publicado no: | Science |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4700591/ https://ncbi.nlm.nih.gov/pubmed/26721998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad4992 |
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