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Molecular mechanism of signal sequence orientation in the endoplasmic reticulum
We have analyzed in vivo how model signal sequences are inserted and oriented in the membrane during cotranslational integration into the endoplasmic reticulum. The results are incompatible with the current models of retention of positive flanking charges or loop insertion of the polypeptide into th...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165631/ https://ncbi.nlm.nih.gov/pubmed/12853479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg361 |
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