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The Hydrophobic Core of the Sec61 Translocon Defines the Hydrophobicity Threshold for Membrane Integration

The Sec61 translocon mediates the translocation of proteins across the endoplasmic reticulum membrane and the lateral integration of transmembrane segments into the lipid bilayer. The structure of the idle translocon is closed by a lumenal plug domain and a hydrophobic constriction ring. To test the...

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Bibliografiske detaljer
Main Authors: Junne, Tina, Kocik, Lucyna, Spiess, Martin
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869373/
https://ncbi.nlm.nih.gov/pubmed/20357000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0060
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