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The Hydrophobic Core of the Sec61 Translocon Defines the Hydrophobicity Threshold for Membrane Integration

The Sec61 translocon mediates the translocation of proteins across the endoplasmic reticulum membrane and the lateral integration of transmembrane segments into the lipid bilayer. The structure of the idle translocon is closed by a lumenal plug domain and a hydrophobic constriction ring. To test the...

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書誌詳細
主要な著者: Junne, Tina, Kocik, Lucyna, Spiess, Martin
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869373/
https://ncbi.nlm.nih.gov/pubmed/20357000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0060
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