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Interaction mapping of the Sec61 translocon identifies two Sec61α regions interacting with hydrophobic segments in translocating chains

Many proteins in organelles of the secretory pathway, as well as secretory proteins, are translocated across and inserted into the endoplasmic reticulum membrane by the Sec61 translocon, a protein-conducting channel. The channel consists of 10 transmembrane (TM) segments of the Sec61α subunit and po...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Kida, Yuichiro, Sakaguchi, Masao
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222115/
https://ncbi.nlm.nih.gov/pubmed/30213864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003219
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