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Role of the Sec61 Translocon in EGF Receptor Trafficking to the Nucleus and Gene Expression

The epidermal growth factor (EGF)-dependent trafficking of the intact EGF receptor to the nucleus and its requirement for growth factor induction of cyclin D and other genes has been reported. Unresolved is the mechanism by which this or other transmembrane proteins are excised from a lipid bilayer...

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Autors principals: Liao, Hong-Jun, Carpenter, Graham
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805100/
https://ncbi.nlm.nih.gov/pubmed/17215517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0802
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