EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

MicroRNAs (miRNAs) are generated by two-step processing to yield small RNAs that negatively regulate target gene expression at the post-transcriptional level(1). Deregulation of miRNAs has been linked to diverse pathological processes, including cancer(2,3). Recent studies have also implicated miRNA...

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Detalhes bibliográficos
Main Authors: Shen, Jia, Xia, Weiya, Khotskaya, Yekaterina B., Huo, Longfei, Nakanishi, Kotaro, Lim, Seung-Oe, Du, Yi, Wang, Yan, Chang, Wei-Chao, Chen, Chung-Hsuan, Hsu, Jennifer L., Wu, Yun, Lam, Yung Carmen, James, Brian P., Liu, Xiuping, Liu, Chang-Gong, Patel, Dinshaw J., Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717558/
https://ncbi.nlm.nih.gov/pubmed/23636329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12080
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